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The dynamic alterations of luminal structures in breast epithelial transformation have profound immunological implications that affect immune surveillance, tumor progression, and treatment responses

10.3390/ijms21207490 313 XuW.YangH.LiuY.YangY.WangP.KimS

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Reports from pharmacologically induced PD models using the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) demonstrate that specific mitochondrial toxins inhibit complex I (CI) activity, thereby promoting degeneration of dopaminergic neurons within the substantia nigra 29